Reliability of Beta-Human Chorionic Gonadotropin in Ectopic Pregnancy

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Human chorionic gonadotropin isoforms in the diagnosis of ectopic pregnancy.

BACKGROUND Early diagnosis of ectopic pregnancy uses ultrasound with serial measurements of total human chorionic gonadotropin (hCG). The objective of this study was to explore the possibility that an isolated measurement of hCG isoforms/subunits rather than total hCG could be used as a single test for ectopic pregnancy. METHODS Total and intact hCG, free hCG beta- and alpha-subunits (hCGbeta...

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Human chorionic gonadotropin profile for women with ectopic pregnancy.

OBJECTIVE To analyze serial human chorionic gonadotropin (hCG) levels in women presenting to the emergency department who were ultimately confirmed to have ectopic pregnancies. METHODS Human chorionic gonadotropin levels were obtained over time until definitive diagnosis. To be included, women had to have at least 2 hCG measurements. Human chorionic gonadotropin curves were characterized and ...

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Ectopic human chorionic gonadotropin beta secretion by epithelial tumors and human chorionic gonadotropin beta-induced apoptosis in Kaposi's sarcoma: is there a connection?

Since it was first claimed in 1995 that human chorionic gonadotropin (hCG) inhibits HIV-associated Kaposi's sarcoma (KS), focus has been lost on establishing a credible hypothesis to explain a novel action ascribed to hCG, which is, after all, a pregnancy hormone. After 7 years, no real progress has been made, and there remains no consensus as to which component of hCG preparations is responsib...

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Correlation of β-human chorionic gonadotropin with ultrasound diagnosis of ectopic pregnancy in the ED.

Women with ectopic pregnancies tend to have lower β-human chorionic gonadotropin (β-hCG) levels than women with intrauterine pregnancies (IUP) [1]. Transvaginal ultrasound (TVUS) is capable of detecting IUPs when β-hCG levels are greater than 1500 mIU/mL, the so-called discriminatory zone [2–4]. When serum β-hCG levels are less than 1500 mIU/mL and no IUP is detected, possibility of ectopic pre...

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Overexpression of beta-human chorionic gonadotropin (β-hCG) is frequently associated with germ cell tumours, especially choriocarcinoma. Ectopic secretion of β-hCG by non-small cell lung cancer is exceptional. We present an exceedingly rare case of pulmonary adenocarcinoma that secretes β-hCG. Our patient is a 62-year-old postmenopausal woman, a nonsmoker, who presented with a six-month history...

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ژورنال

عنوان ژورنال: JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH

سال: 2018

ISSN: 2249-782X

DOI: 10.7860/jcdr/2018/35825.11873